I can only speak for Devcon topcoat, but would assume that the same is true for the other topcoats.....yes. If you use Devcon, the coated lure needs to be turned for at least twenty minutes, maybe longer. You still can't touch the lure after twenty minutes (don't try for at least six or seven hours if not longer).
But if you are just making one or two at a time, you might not even bother with the turning wheel. A set of locking forceps can grip the line tie so you can turn it by hand.
If you don't turn the lure, you'll get dimples, incomplete coverage, a superthick coat on the lower portion of the lure, and little to no coverage on the upper end. Plus it will likely drip on you and make a big mess.
You need to turn, just be careful not to drop the thing whether turning by hand or clipping to your wheel.