+1.... I don't post here much, but this is what I've found.
First of all, what DN top coat are you using? Do you use heat to cure the DN and your Createx? I use the moisture cure (I think its called S-81) and have had the same issues in the past. What caused my problems was that I use a couple thermostat controlled 100w lights in a box to maintain a temp of 100deg. I was having wrinkling on lures that had been painted with darker paints (black, green, blue, etc.) What was happening was the heat from the lights (direct light not diffused) was being absorbed faster into the darker colors and after dipping and hanging in the 100deg box the DN would start to cure too fast from the excessive heat absorbed by those colors. As the DN ran down the body, It would create wrinkles anywhere the darker colors were present. I also had the lures sitting in the box (at 100deg) before they were dipped. Now I don't preheat the lures that have the dark colors on them, I place them into the box only after being dipped. I also now lower the temperature for the first 1/2 hour that they hang. I dip most lures at least twice this way and have had no further issues.
I know this is a little different than what you described, but it sounds like your pearls are not fully set/cured.